Vaspin Serpin A12 ELISA Kit, Antibody,Protein |
A biomarker for cardiovascular diseases and metabolic syndrome |
Alternative name:
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Visceral adipose tissue-derived serine protease inhibitor
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Visceral adipose-specific serpin
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Serpin A12
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Investigation of vaspin level in patients with acute ischemic stroke
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Background
Cerebrovascular event is a clinical condition characterized by symptoms and findings pertaining to loss of focal cerebral function because of the vascular causes. Atherosclerosis has a forefront role in the pathogenesis of stroke. Inflammation has an important place in the formation of atherogenesis and atherosclerosis. Visceral adipose tissue–derived serpin (vaspin) is a new adipokine, which is identified recently, associated with obesity and diabetes and also has a proinflammatory characteristic. This study was intended to investigate the relation between vaspin and stroke and stroke and other risk factors.
Methods
A total of 50 patients with stroke, as 28 men (56%) and 22 women (44%), and a total of 50 healthy individuals, as 25 men (50%) and 25 women (50%), were enrolled in the study. Blood samples were taken in the acute period (first 48 hours) in the patient group, and serum vaspin levels were measured. Vaspin level was also measured in the control group. The association of vaspin with the lipid parameters, gender, and the severity of internal carotid artery (ICA) stenosis in the patient group was evaluated. Stenotic plaques in ICA were classified as normal, mild (stenosis under 50%), moderate (stenosis 50%-69%), severe (stenosis 70%-99% to preocclusion), and occlusion.
Results
No statistically significant difference was found between 2 groups in terms of age and gender (P > .05). Vaspin levels were found to be significantly higher in the patient group (164.73 ± 153.76 ng/mL) compared with the control group (116.21 ± 34.60 ng/mL) (P < .05). However, no relation was established between vaspin level and the severity of ICA stenosis.
Conclusions
Vaspin levels have been shown to increase in acute ischemic stroke patients. The increased vaspin levels may vary depending on several factors in acute period of ischemic stroke |
Cura HS et al. J Stroke Cerebrovasc Dis. 2014 Mar;23(3):453-6. doi: 10.1016/j.jstrokecerebrovasdis.2013.03.023. Epub 2013 Apr 14.
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Code No.: SK00560-06
Size: 96 T
Price: $460.00 USD
Standard Range:62-4000 pg/ml
Sensitivity:30 pg/ml
Speificity:Human
Sample Type: serum, EDTA plasma
Sample requres: 100 ul per well
IntraCV: 6-8%
InterCV: 10-12%
Protocol: PDF |
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Code No.: SK00560-01
Size: 96 T
Price: $420.00 USD
Standard Range:312-20000 pg/ml
Sensitivity:50 pg/ml
Speificity:Human
Sample Type: serum, EDTA plasma
Sample requres: 100 ul per well
IntraCV: 4-7%
InterCV: 8-10%
Protocol: PDF |
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Code No.: SK00560-03
Size: 96 T
Price: $420.00 USD
Standard Range:1.6-1000 ng/ml
Dynamic Range: 1.6-1000 ng/ml
Sensitivity:0.097 ng/ml
Speificity:M, R, H
Sample Type: serum, EDTA plasma
Dilution Factor: 2
Sample requres: 60 ul
IntraCV: 6-8%
InterCV: 10-12%
Protocol: PDF |
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Code No.: A00560-02-100
Size: 100 ug
Price: $260.00 USD
Clone No.: 1H12E11
Host: Mouse
Antigen: human vaspin rec..
Ab Type: Purified Monoclonal IgG
Purification: Protein G
Applications: E, WB
Working Dilution: 2-4 ug/ml)
Data Sheet: PDF |
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Code No.: A00560-04-100
Size: 100 ug
Price: $260.00 USD
Clone No.: 2E12G2
Host: Mouse
Antigen: human vaspin rec..
Ab Type: Purified Monoclonal IgG
Purification: Protein G
Applications: E, WB
Working Dilution: 2-4 ug/ml)
Data Sheet: PDF |
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Code No.: A00560-05-100
Size: 100 ug
Price: $260.00 USD
Clone No.: 2H12E10
Host: Mouse
Antigen: human vaspin rec..
Ab Type: Purified Monoclonal IgG
Purification: Protein G
Applications: E, WB
Working Dilution: 2-4 ug/ml)
Data Sheet: PDF |
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Code No.: A00560-06-100
Size: 100 ug
Price: $260.00 USD
Clone No.: 1G5D12
Host: Mouse
Antigen: human vaspin rec..
Ab Type: Purified Monoclonal IgG
Purification: Protein G
Applications: E, WB
Working Dilution: 2-4 ug/ml)
Data Sheet: PDF |
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Code No.: A00560-07-100
Size: 100 ug
Price: $260.00 USD
Clone No.: 1A2B2
Host: Mouse
Antigen: human vaspin rec..
Ab Type: Purified Monoclonal IgG
Purification: Protein G
Applications: E, WB
Working Dilution: 2-4 ug/ml)
Data Sheet: PDF |
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Code No.: A00560-01-100
Size: 100 ug
Price: $220.00 USD
Host: Rabbit
Antigen: human vaspin.
Ab Type: Polyclonal IgG
Purification: Protein A
Applications: E, IHC, WB
Working Dilution: IHC 5 ug/ml; WB 1ug/ml)
Data Sheet: PDF |
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Code No.: A00560-01-100
Size: 100 ug
Price: $220.00 USD
Host: Rabbit
Antigen: human vaspin.
Ab Type: Polyclonal IgG
Purification: Protein A
Applications: E, IHC, WB
Working Dilution: IHC 5 ug/ml; WB 1ug/ml)
Data Sheet: PDF |
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Code No.: A00560-03-100
Size: 100 ug
Price: $220.00 USD
Host: Rabbit
Antigen: mouse vaspin.
Ab Type: Polyclonal IgG
Purification: Protein A
Applications: E, IHC, WB
Working Dilution: IHC 5 ug/ml; WB 1ug/ml)
Data Sheet: PDF |
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Code No.: 00560-01-100
Size: 100 ug
Price: $360.00 USD
Protein ID:Q81W75
Gene ID: 145264
MW: 49 KD
Tag: His Tag on N-Terminus
Expressed: E. Coli
Purity: 95%
Data Sheet: PDF |
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