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FGF23 ELISA kit , Antibody, Recombinant
A biomarker for osteoporosis and cardiovascular calcification
Order FGF23 Products Please Checkout 
FGF23 induces left ventricular hypertrophy
Chronic kidney disease (CKD) is a public health epidemic that increases risk of death due to cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of cardiovascular disease in individuals with CKD. Elevated levels of FGF23 have been linked to greater risks of LVH and mortality in patients with CKD, but whether these risks represent causal effects of FGF23 is unknown. Here, we report that elevated FGF23 levels are independently associated with LVH in a large, racially diverse CKD cohort. FGF23 caused pathological hypertrophy of isolated rat cardiomyocytes via FGF receptor–dependent activation of the calcineurin-NFAT signaling pathway, but this effect was independent of klotho, the coreceptor for FGF23 in the kidney and parathyroid glands. Intramyocardial or intravenous injection of FGF23 in wild-type mice resulted in LVH, and klotho-deficient mice demonstrated elevated FGF23 levels and LVH. In an established animal model of CKD, treatment with an FGF–receptor blocker attenuated LVH, although no change in blood pressure was observed. These results unveil a klotho-independent, causal role for FGF23 in the pathogenesis of LVH and suggest that chronically elevated FGF23 levels contribute directly to high rates of LVH and mortality in individuals with CKD.
Christian Faul et al. J Clin Invest. 2011, doi:10.1172/JCI46122.
Human FGF-23 ELISA Kit from aviscera bioscience

Human FGF23 ELISA
Code No.: SK00147-09
Size: 96 T
Price: $460.00 USD
Standard Range:31.25-2000 pg/ml
Sensitivity:15 pg/ml
Sample Type: cell culture, serum, EDTA plasma
Sample requres: 100uL per well
IntraCV: 6-8%
InterCV: 10-12%
Protocol: PDF

anti human FGF23 IgG A00147-01-100 from aviscera bioscience
Anti Human FGF-23 IgG
Code No.: A00147-01-100
Size: 100 ug
Price: $260.00 USD
Host: Rabbit
Antigen: human FGF-23 (25-179).
Ab Type: Polyclonal IgG
Purification: Protein A
Applications: E, IHC,
Working Dilution: IHC 2-4 ug/ml)
Data Sheet: PDF
Human FGF23 C-Terminal Peptide (18-251)
Code No.: 00147-06-100
Size: 96 T
Price: $360.00 USD
Sequence: 18Ser-251ILe
Protein ID :Q9GZV9
Gene ID : 8074
Tag; His Tag on N-terminus
Data Sheet: PDF
Human FGF23 N-Terminal Fragment (25-179) His Tag Rec
Code No.: 00147-08-100
Size: 96 T
Price: $360.00 USD
Protein ID :Q9GZV9
Gene ID : 8074
Tag; His Tag on N-terminus
Data Sheet: PDF
  Anti Human FGF23 N-Terminal  Antibody
Code No.: A00147-01-100
Size: 100 ug
Price: $260.00 USD
Host: rabbit
Antigen: human FGF23 (25-179).
Ab Type: Purified IgG
Purification: Protein G
Applications: E, IHC, WB
Working Dilution: 0.1ug/ml)
Data Sheet: PDF
Anti Human FGF23 C-Terminal  Monoclonal Antibody
Code No.: A00147-06-100
Size: 100 ug
Price: $220.00 USD
Host: Mouse
Antigen: human FGF23 C Terminal Fragment.
Ab Type: Purified IgG
Purification: Protein G
Applications: E
Working Dilution: 0.1ug/ml)
Data Sheet: PDF
Anti Human FGF23 C-Terminal  Monoclonal Antibody
Code No.: A00147-07-100
Size: 100 ug
Price: $220.00 USD
Host: Mouse
Antigen: human FGF23 C Terminal Fragment.
Ab Type: Purified IgG
Purification: Protein G
Applications: E
Working Dilution: 0.1ug/ml)
Data Sheet: PDF
  Mouse FGF-15 His Tag Rec
Code No.: 00659-03-100
Size: 96 T
Price: $360.00 USD
Protein ID :O35622
Gene ID : 14170
Tag; His Tag on N-terminus
Data Sheet: PDF
Soluble and secreted Klotho ELISA Kit

 

 

More FGF family Proteins

 

Name
Code No.
Size
Price ($)
FGF-23 (Human) ELISA Kit
96 T
460
FGF-23 (Human) ELISA Kit
192 T
840
FGF-23 (Human) ELISA Kit
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1950
FGF-23   (Human)Recombinant
00147-02-100
100 ug
390.00
FGF-23 C Terminal  (Human)Recombinant
10 ug
120.00
FGF-23 C Terminal  (Human)Recombinant
20 ug
210.00
FGF-23 C Terminal  (Human)Recombinant
100 ug
360.00
FGF-23 N Terminal  (Human)Recombinant
100 ug
360.00
FGF-15 (Mouse) Rec
100 ug
360.00
Anti Human FGF-23 N Terminal Fragment IgG
100 ug
260.00
Anti Human FGF-23 N Terminal Fragment IgG Biotinylated
50 ug
290.00
Anti Human FGF-23 IgG
100 ug
260.00
Anti FGF-23 C Terminal  (Human)  Monoclonal Antibody
100 ug
220.00
Anti FGF-23 C Terminal  (Human)  Monoclonal Antibody
100 ug
220.00
Anti FGF-23 C Terminal  (Human)  Monoclonal Antibody Biotinylated
50 ug
290.00
Anti FGF-23 C Terminal  (Human)  Monoclonal Antibody Biotinylated
50 ug
290.00